Gao et al reported that acupuncture can be used as an alternative treatment to improve cognitive function and QoL of patients with ITN.


116 patients enrolled: acupuncture intervention group (n = 62) and sham control group (n = 54).


Clinical pain, cognitive function, and quality of life (QoL) assessed with the 36-Item Short Form Health Survey (SF-36) , at the initial time of treatment, at the end of treatment, and 6 weeks after the treatment.


  1. pain intensity, headache, and generalized body pain significantly decreased both at the end of treatment and after 6 weeks of treatment compared with initial time
  2. the scores of the cognitive tests (Mini-Mental State Examination, Trail Making Test, Verbal Fluency Test, tracing score, and memory score) and five aspects of the SF-36 assessment (role emotional, general health, body pain, role physical, and mental health scores) significantly improved at the end of treatment compared with the initial time, and
  3. after 6 weeks of treatment, the Mini-Mental State Examination, memory score, and Trail Making Test-A score and four aspects of the SF-36 assessment (vitality, bodily pain, mental health, and role physical) significantly improved when compared with the end of treatment.

Cite: Gao, J., Zhao, C., Jiang, W., Zheng, B., & He, Y. (2019). Effect of Acupuncture on Cognitive Function and Quality of Life in Patients With Idiopathic Trigeminal Neuralgia. The Journal of nervous and mental disease, 207(3), 171-174.